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Pregnancy

HCG Levels - Pregnancy or Menopause

20 replies

flumpybono73 · 01/07/2008 21:42

Hi, I've recently taken 2 pregnancy tests which have shown a very faint line. However, my LH and FSH levels indicate that I have premature ovarian failure, so I'm not sure whether I could be pregnant or that the tests are very sensitive to HCG as a result of the menopause??!! Any advice would be grateful as this is doing my head in.

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OracleInaCoracle · 01/07/2008 21:43

hmm, best thing to do would be to see your gp imho. not sure how menopause affects HCG (pretty sure it doesnt)

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flumpybono73 · 01/07/2008 21:47

Thanks lissielou, I'm off to the gp's tomorrow. I'm actually hoping that it's positive (pregnancy) but have a niggle that I'm probably not

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QueenyEisGotTheBall · 01/07/2008 21:51

as far as i know menopause doesnt make hcg levels change only pregnancy or a fertilised egg does this. i would go and see your GP asap if i were you good luck
xx ei xx

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SlightlyMadSweet · 01/07/2008 21:54

Apparently there are other causes of raised hCG, they sound pretty rare though.

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flumpybono73 · 01/07/2008 22:02

I really don't know. I did sainsbury's own tests, but the line is really really faint, so i wasn't sure whether that meant they just picked up a wee bit of hcg

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SlightlyMadSweet · 01/07/2008 22:03

I didn't mean to say it wasn't a pg.

A positive pg test doesn't have to be bright.

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flumpybono73 · 01/07/2008 22:09

I feel like a right gimp as I keep looking at what is a v.faint line. i'm tempted to do another one but might leave it til the morning. the thing is, i don't even feel preggers!

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mumofnone · 01/07/2008 23:56

I was diagnosed with POF 9 years ago... and expecting my first any day now! Ironically, I was taking the pill as a form of HRT, so you never know -- anything is possible!

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nappyaddict · 02/07/2008 00:36

do you know how sensitive the tests are? i know tests that have a sensitivity of 10 miu/ml can be too sensitive for women going through the menopause and give a positive result when they are not pregnant.

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nappyaddict · 02/07/2008 16:18

just found this for you:

A non-pregnant women usually has 0-2 mIU/mL? of hCG in her blood, with 0.5? being the average. (Peri- and post-menopausal woman can have up to 12 mIU/mL!)? There are two types of pregnancy blood tests: quantitative, which measures the quantity of hCG in the blood in numbers, and qualitative, which measures the quality of hCG (either positive reaching a predetermined cutoff point set by the lab, or negative.) A level of 5 or less is usually deemed "not pregnant" by labs. Some labs use a cutoff point of 20 or 25 as a "positive" threshold. In other words, they do something very similar to peeing on a stick except they use a test designed for blood instead of urine.

Most pregnancy tests are more sensitive than advertised (though not all tests, even among the same brand, are equally sensitive. If there are 3 tests in a box, they will all detect AT LEAST the advertised sensitivity say, 25 mIU/mL but one may detect 17, another 13, another 6.) Consumer Reports once found that First Response Earliest Result was capable, on occasion, of detecting as little as 4.5 mIU/mL. In other words, home pregnancy tests are capable of detecting very, very small amounts of hCG and detecting pregnancies very, very early.

The important thing to remember in this scenario is that when an embryo secretes hCG, it is metabolized into the blood first, and takes another day or two to reach the urine. Likewise, when hCG dissipates, it leaves the blood first. So, when a miscarriage occurs, the hormone will linger in the urine for a short while after it is gone from the blood.

So, it is entirely possible for a pregnancy test to detect a pregnancy and turn positive, followed by a negative blood test-- simply because the embryo has produced a small amount of hCG before dying. That small amount is enough to trigger a positive HPT, and small enough to dissipate from the blood stream by the time a blood test is conducted.

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flumpybono73 · 02/07/2008 21:08

Thanks nappyaddict - i put in a urine sample at the docs this morning, so should find out tomorrow. I did another test (should get shares in the things) with yet another line, this time a wee bit darker.. so I'm confused but reckon I won't be

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nappyaddict · 02/07/2008 23:56

I would insist on a blood test. the docs test will only be able to tell you what you've already seen on a HPT.

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minster · 03/07/2008 08:49

Also, the urine tests at the doctors are far less sensitive (some only detect 100miu of HCG) than commercial ones (FRER can detect down to 12.5miu) - if you're getting faint lines it may well be negative at GP & as far as they are concerned that'll be the end of the story. An EPU will do quantitive (& repeat HCG) levels & that will give you a much better idea of what is going on.

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Buda · 03/07/2008 08:53

Oh fingers crossed for you! I have read so many threads here where a faint line is still a line!

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nappyaddict · 03/07/2008 15:07

FRER are on bogof in boots at the minute.

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flumpybono73 · 03/07/2008 21:00

The saga continues... my urine results from the docs was a 'weak positive'. I'm phoning my gp up tomorrow to see what to do next, but will ask for a blood test. Thanks for all the advice folks

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flumpybono73 · 03/07/2008 21:01

btw wot are epu and frer?

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SlightlyMadSweet · 03/07/2008 21:34

epu = early pregnancy unit.
frer = first response ???? ???? (pg test brand).

If your lines are getting stronger I think it makes pg more likely than the other possibilities TBH.

Congratulations

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nappyaddict · 03/07/2008 22:41

frer = first response early result test

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flumpybono73 · 04/07/2008 12:15

spoke to doc today who said he doesn't think I'm pregnant but need to repeat test on monday. I'm going to get yet another hpt test tho to see if line is stronger

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