IVF cycle 1 failed - what to expect next?

[pinkapples]

Hello ladies, been on a few threads now just hoping for a bit of advice really. I've had 8 rounds of clomid I think (maybe 7 can't remember) 1 lap and dye, 4 cycles of ovulation induction resulting in a pregnancy on the 4th cycle but ended in miscarriage at 7 weeks and our first shot at IVF has just failed. 9 mature eggs only 1 fertilised day 2 transfer of a good 3 cell (although they like them to be 4 cell I'm told)

Nurse mentioned about ICSI as only one of the nine fertilised. I have been drinking 1 cup of tea a day (2 at the weekend) and doing not much else tbh progesterone gel daily aswel since transfer. AF came on Wednesday 12dp2dt so absolutely gutted but have come
To terms with the fact this ones a bust...

I guess I just want to hear some hope... How many times have people done IVF/ICSI if the ICSI doesn't work then what's the next thing we do? I'm only 24 but have been in treatment for 2 years, trying for 4 as we knew it would be hard hubby is 28 this year and we've been together 6 years...

Sorry for the ramble any help/advice would be fab x x

[freelancescientist]

Firstly I am sorry your cycle was unsuccessful.
ICSI would be the logical next step from the clinic's point of view.
It seems as if there is a problem with fertilisation if only one of 9 eggs fertilised, and ICSI can help if sperm and egg are not binding together normally.
What this would do is hopefully get you a few more embryos so there is then a choice of what to replace (and maybe some to freeze for another go as well), which increases your chances of getting pregnant.
If the ICSI doesn't work in terms of getting you more embryos (ie if the fertilisation rate is still poor) then your options are limited to donor eggs, sperm or donated embryos, or trying again with the understanding that you just don't make that many embryos.
If it doesn't work in that you have a better fert rate but you don't get pregnant then that may be a case where the clinic considers investigating you for recurrent implantation failure.
There are still places to go and things to try if you are up for it. Maybe take a little time off to let your body recover from this cycle, see the staff at the clinic and take it from there.

[pinkapples]

Thanks for the advice I'm hopeful that the ICSI should give us a chance as my hubby is fine no issues all good woohoo and my only problem was supposed to be getting the eggs to ovulate but who knows there could be other issues lurking fingers crossed we can get on the next cycle quick x

[Ilovemytwins]

Hi,

I am so sorry about ur unsuccessful ivf and your miscarriage. I was in a similar position to you, so hopefully this will give you some hope.

We tried for 6 1/2 years, 9 months on clomid two rounds of iui which all failed. Our first ivf failed, I got 10 eggs but only one fertilised, and that was a 3 cell. So we decided to try icsi, this time I got 15 eggs. 6 were good enough to use, 3 fertilised and all developed to 6 cells. I had a double transfer and one frozen. And I am now here with 5 month old twin girls.

Please don't give up hope, we did find icsi to be the better option. I relaxed more this time round too, I drank if I wanted and carried on as normal. Ate lots of brazil nuts and coconut, as this is supposed to help.

Wishing you the best of luck, I hope you get it baby. :)
Xxxxx

[Ilovemytwins]

That last bit was, I hope you get ur baby! Not get it baby. Lol. Xx

[thaliablogs]

If husband is fine then not sure why ICSI is going to do you any good - it is helpful when there aren't many good sperm around. I would ask what problem they think they are solving with ICSI. What do they think the fert failure is about? Were the eggs immature? Did you overstim?

Lots of people's first cycle fails, so you should definitely not lose hope. I did three cycles and one frozen cycle (with 2 miscarriages) before dd arrived, and another failed cycle before my son, so one failure is definitely not the end, although of course it feels devastating.

[pinkapples]

The eggs were mature and hubby is fun they said all the sperm went to the one egg they didn't seem interested in the others so by doing th ICSI they reckon they should at least all fertilise