1)American Gods -Neil Gaiman
2)The Sandman- Neil gaiman
3) The Watchmen- Alan Moore
4) Weaveworld- Clive Barker
5)Handmaids Tale - Margaret Atwood
6)The Stand- Steven King
7)The Time Travellers Wife- Audrey Niffenegger
8)Harry Potter
9) His Dark Materials
10) Something by Marian Keyes

As others have said, it would vary depending on my mood but here's my list atm:

1) A Handmaid's Tale - Margaret Atwood
2) His Dark Materials - Philip Pullman
3) Rebecca - Daphne Du Maurier
4) The Blind Assassin - Margaret Atwood
5) Memoirs of a Geisha - Arthur Golden
6) Rita Hayworth & the Shawshank Redemption - Stephen King
7) The Dark Tower series - Stephen King
8) The Stand - Stephen King
9) North and South - Elizabeth Gaskill
10)Sense and Sensibility - Jane Austen

I am cheating a bit as His Dark Materials has 3 books and Dark Tower 7

Okay, books I've been mildly obsessed with at various times:

1) Some Tame Gazelle - Barbara Pym
2) Mapp and Lucia - E. F. Benson
3) In Ruins - Christopher Woodward (non-fiction)
4) Ex Libris - Anne Fadiman (non-fiction)
5) Travels among the Tourists - Taras Grescoe (non-fiction)
6) Thank Heaven Fasting - E. M. Delafield
7) The Ark of the Covenant - Tudor Parfitt (non-fiction)
8) Persuasion - Jane Austen
9) The Bagthorpe saga - Helen Cresswell (cheating as there are 10 books)
10)Crampton Hodnet - Barbara Pym

Yes, I have weird taste.

Fugitive Pieces - Anne Michaels
Crow Lake - Mary Lawson
Never Let Me Go - Kazuo Ishiguro
Atonement - Ian McEwan
The Amateur Marriage - Anne Tyler
Perfect Match - Jodi Picoult
The Good Mother - Sue Miller
To Kill a Mockingbird - Harper Lee
Overnight to Innsbruck - Denyse Woods
Rita Hayworth and The Shawshank Redemption - Stephen King

these are for the weird minded, generally all of clive barker books i would recommend. but here are my few:

1. Sacrement- Clive barker
2. books of blood - Clive Barker
3.Child called It - Dave Pelzer
4. Lost Boy - Dave Pelzer
5. man named Dave - Dave Pelzer
6. memoirs of a geisha- Aurthur Golden
7. lord of the flies - William Golding
8. the dice man - luke rhinehart (fantastic true stories)
9. the search for the dice man- luke rhinehart
10.dean koontz also, all of them.

Oooh - cool thread idea! I think my list would change everyday, but here we go as a start! (not in rank order)

1. Jane Eyre - Bronte
2. Madame Bovary - Flaubert
3. Crime & Punishment - Dostoyevsky
4. When Hitler stole pink rabbit (whole trilogy)- Judith kerr
5. Oliver Twist - Dickens
6. The Shell Seekers - Pilcher
7. Of Mice and Men
8. All Harry Potters
9. Captain Corelli's Mandolin, Louis de Bernieres
10.Memoirs Of A Geisha, Arthur Golden

Oops did 12, not 10!

1. A Prayer for Owen Meany - John Irving
2. A Fine Balance - Rohinton Mistry
3. Madame Bovary - Flaubert
4. Great Expectations - Dickens
5. Vanity Fair - Thackeray
6. A Town Like Alice - Neville Chute
7. To Kill a Mocking Bird - Harper Lee
8. The Franchise Affair - Josephine Tey
9. Gone with the Wind - Margaret Mitchell
10. Pride and Prejudice - Austen
11. Tess of the D'Urbervilles - Hardy
12. Wild Swans - Chang

Mind you, I think I'd probably have a variation on this list every day as it depends what mood I'm in (and which books I have probably forgotten about!)

and you find out you've only read 12 books on the list and feel totally inadequate/unnaturally angry at the predominance of Jane Austen and JK Rowling? What would be on your "10 Books I think are awesome and you have to read" list?
I'll start:
1. I know why the caged bird sings, or even, the whole series, by Maya Angelou. Very good if you're feeling down, as once you've compared your problems to a black woman who grew up in Mississippi who had to move once her brother witnessed a lynching, was sexually abused by her step father, had to work as a Madam in a brothel, being shunted all over the countryside etc. etc. your life doesn't seem that troubling anymore.
2. Anna Karenina. It's just amazing. And it reminds you of why women fought for equal rights
3. The Plague by Albert Camus. Very good pre-Swine Flu 2009 reading
4. The Unbearable Lightness of Being by Milan Kundera. Very clever book. There's a great bit about different people's vocabulary
5. Little Women
6. Anne of Green Gables
7. Hunchback of Notre Dame - very swashbuckling and exciting
8. Catch 22 - I know there are tons of people on MN who'd disagree with me on this one, but I like it.
9. To Kill a Mockingbird, Harper Lee- one of the greatest books ever written
10. In Cold Blood, Truman Capote - he was Harper Lee's childhood friend (Dill is based on him!). But anyway, this is quite a chilling book but an interesting look into the mind of murderers.